Blog
What Makes a High-Quality Hit in Early Drug Discovery?
Why enhancing confidence in primary screening is critical to translational success—and how...
What Is Unbiased Selectivity Profiling? A CETSA®-Based Approach to Drug Discovery
In pursuing safer and more efficacious therapeutics, comprehensively characterizing how sm...
Accelerating Drug Discovery with Proteome-Wide CETSA® Profiling: Why Timing Is Everything
At Pelago Bioscience, we work with drug discovery teams to optimize their approach to targ...
Why Drug Candidates Fail During Development: The Challenges of Target Engagement
Importance of Target Engagement in Drug Discovery Despite billions invested in drug develo...
Using CETSA® to Measure Target Engagement in Whole Blood
Validating target engagement is a crucial step in drug development, helping us understand ...
Are Your Degraders Delivering on Their Promise?
Biologically Relevant Insights for Protein Degraders with CETSA® Targeted protein de...
Is Your Hit on Target?
How to Confidently Validate Drug Discovery Hits A blog post High-throughput screening...