Unbiased Selectivity Profiling, CETSA with MS detection 

Another really good title Selectivity in drug development is an essential prerequisite for the generation of lead candidates. The limited number of proteins profiled in traditional panels results in a biased selectivity assessment. Pelago Bioscience has established a standardized selectivity profiling assay, based on the Cellular Thermal Shift Assay with mass spectrometric (MS) detection, that enables discrimination between selective and more promiscuous binding molecules at the proteome level. References