Pinpoint the Right Targets
Identifying the right molecular target is a critical step in drug development—it sets the stage for everything that follows. A comprehensive understanding of how a target can be modulated and its influence on disease progression increases the odds of success and minimizes the risk of costly failures later.
Our CETSA® technology examines how compounds interact with the entire proteome in living cells. This unbiased, whole-proteome profiling gives a clear picture of both direct and off-target effects, as well as the cellular pathways responsible for driving disease, helping you make better, more informed drug discovery decisions from the very start.
Key benefits
- Proteome-Wide Insights: Get a complete view of how your compounds engage with proteins across the cell
- Early Off-Target Detection: Spot potential issues before they become costly problems
- Pathway Discovery: Identify key cellular pathways influenced by your treatment
How It Works
CETSA measures changes in protein stability in live cells when exposed to a drug. By tracking these shifts across the entire proteome, we can reveal direct interactions and unexpected off-target effects. This data helps you understand which pathways are being activated—or disrupted—giving you the information you need to advance your discovery program confidently.
Discover Targets That Set You Up for Success
Get deeper insights into your compounds’ behavior—and make more intelligent choices from the beginning. Contact our team today to learn how CETSA can support your target identification strategy.
Get in touch
Contact us to learn more, to book a meeting or request a quote.